OBESITY ASSOCIATED ATRIAL FIBRILLATION: EPICARDIAL FAT TISSUE IN ETIOPATHOGENESIS

Epicardial Fat and Atrial Fibrillation: A Review.

Atrial fibrillation (AF) is a progressive disorder that increases with age. Obesity is an important risk factor for AF. Pericardial fat is an active adipose tissue in close proximity to the heart and has been shown to be a risk factor for structural as well as coronary artery disease independent of body mass index. Recent studies suggest a role of epicardial fat in atrial remodeling as well as ...

Epicardial adipose tissue and atrial fibrillation.

Atrial fibrillation (AF) is the most frequent cardiac arrhythmia in clinical practice. AF is often associated with profound functional and structural alterations of the atrial myocardium that compose its substrate. Recently, a relationship between the thickness of epicardial adipose tissue (EAT) and the incidence and severity of AF has been reported. Adipose tissue is a biologically active orga...

Periatrial Epicardial Fat Is Associated with Markers of Endothelial Dysfunction in Patients with Atrial Fibrillation

BACKGROUND Epicardial adipose tissue (EAT) is associated to atrial fibrillation (AF) burden and outcome after AF ablation. We intended to determine whether global or local EAT is associated with systemic and/or left atrial (LA) inflammation and markers of endothelial dysfunction in AF patients. METHODS AND RESULTS Total, atrial, and ventricular EAT volume (EAT total, EAT atrial, EAT ventricul...

Epicardial adipose tissue and neural mechanisms of atrial fibrillation.

Epicardial Adipose Tissue Thickness and Ablation Outcome of Atrial Fibrillation

OBJECTIVES Epicardial fat was closely related to atrial fibrillation (AF). Transthoracic echocardiography (TTE) has been proposed to be a convenient imaging tool in assessing epicardial adipose tissue (EAT). The goal of the present study was to investigate whether the EAT thickness measured on TTE was a useful parameter in predicting procedural outcomes of AF ablations. METHODS AND RESULTS A ...